| Date | Location | Result | |
| 03/26/21 | Columbus, OH | Lubbock Christian 69, Drury 59 | Box score |
| 03/24/21 | Columbus, OH | Drury 74, Lander (S.C.) 65 | Box score |
| 03/23/21 | Columbus, OH | Drury 74, Charleston (WV) 66 | Box score |
| 03/15/21 | Springfield, MO | Drury 88, Ashland 69 | Box score |
| 03/13/21 | Springfield, MO | Drury 66, Truman State 51 | Box score |
| 03/12/21 | Springfield, MO | Truman State 55, Northwood 42 | Box score |
| 03/07/21 | Springfield, MO | Drury 76, Truman State 60 | Box score |
| 03/06/21 | Kirksville, MO | Truman State 68, William Jewell 52 | Box score |
| 03/06/21 | Springfield, MO | Drury 75, Missouri-St. Louis 62 | Box score |
| 03/03/21 | Springfield, MO | Drury 70, Indianapolis 66 | Box score |
| 03/03/21 | Kirksville, MO | Truman State 76, Maryville 73 | Box score |
| 03/03/21 | Romeoville, IL | Missouri-St. Louis 69, Lewis 67 | Box score |
| 02/27/21 | Springfield, IL | Missouri S&T 82, Illinois Springfield 79 | Box score |
| 02/27/21 | Liberty, MO | William Jewell 72, Rockhurst 66 | Box score |
| 02/27/21 | Romeoville, IL (Neil | Lewis 90, Maryville 77 | Box score |
| 02/27/21 | Kirksville, MO | Truman State 47, Southwest Baptist 41 | Box score |
| 02/27/21 | Quincy, IL | Drury 93, Quincy 74 | Box score |
| 02/27/21 | Indianapolis, IN | Lindenwood 65, Indianapolis 64 | Box score |
| 02/25/21 | Quincy, IL | Southwest Baptist 69, Quincy 50 | Box score |
| 02/25/21 | Indianapolis, IN | Maryville 59, Indianapolis 58 | Box score |
| 02/25/21 | Romeoville, IL (Neil | Lewis 93, Missouri S&T 71 | Box score |
| 02/25/21 | Kirksville, MO | Truman State 76, Rockhurst 69 | Box score |
| 02/25/21 | Springfield, IL | Drury 75, Illinois Springfield 57 | Box score |
| 02/23/21 | Springfield, MO | Drury 79, William Jewell 44 | Box score |
| 02/23/21 | Saint Charles, MO | Lindenwood 67, Quincy 58 | Box score |
| 02/20/21 | Kansas City, MO | Rockhurst 71, Quincy 55 | Box score |
| 02/20/21 | Saint Charles, MO | Lindenwood 75, McKendree 73 | Box score |
| 02/20/21 | Bolivar, MO | Illinois Springfield 63, Southwest Baptist 58 | Box score |
| 02/20/21 | Rolla, MO | Indianapolis 79, Missouri S&T 72 | Box score |
| 02/20/21 | Springfield, MO | Drury 100, Lewis 57 | Box score |
| 02/18/21 | Kansas City, MO | Illinois Springfield 61, Rockhurst 56 | Box score |
| 02/18/21 | St. Louis, MO | Maryville 87, McKendree 84 | Box score |
| 02/18/21 | Liberty, MO | William Jewell 62, Quincy 54 | Box score |
| 02/18/21 | Saint Charles, MO | Missouri-St. Louis 74, Lindenwood 70 | Box score |
| 02/18/21 | Bolivar, MO | Lewis 85, Southwest Baptist 60 | Box score |
| 02/16/21 | Liberty, MO | William Jewell 77, Lindenwood 68 | Box score |
| 02/16/21 | Lebanon, IL | McKendree 71, Illinois Springfield 68 | Box score |
| 02/13/21 | Lebanon, IL | McKendree 86, Missouri S&T 81 | Box score |
| 02/13/21 | Indianapolis, IN | Indianapolis 77, Southwest Baptist 66 | Box score |
| 02/13/21 | Springfield, IL | William Jewell 71, Illinois Springfield 61 | Box score |
| 02/13/21 | St. Louis, MO | Maryville 73, Missouri-St. Louis 70 | Box score |
| 02/13/21 | Evansville, IN | Drury 93, Southern Indiana 64 | Box score |
| 02/11/21 | Indianapolis, IN | Indianapolis 88, Rockhurst 72 | Box score |
| 02/11/21 | Saint Charles, MO | Maryville 70, Lindenwood 58 | Box score |
| 02/11/21 | St. Louis, MO | Missouri-St. Louis 77, Missouri S&T 54 | Box score |
| 02/11/21 | Romeoville, IL | William Jewell 95, Lewis 77 | Box score |
| 02/11/21 | Lebanon, IL | Drury 91, McKendree 76 | Box score |
| 02/09/21 | Springfield, IL | Illinois Springfield 56, Lindenwood 46 | Box score |
| 02/08/21 | Kansas City, MO | Lewis 75, Rockhurst 55 | Box score |
| 02/06/21 | Bolivar, MO | McKendree 72, Southwest Baptist 62 | Box score |
| 02/06/21 | Quincy, IL | Illinois Springfield 100, Quincy 99 | Box score |
| 02/06/21 | Kirksville, MO | Truman State 83, Lewis 74 | Box score |
| 02/06/21 | Rolla, MO | Lindenwood 80, Missouri S&T 72 | Box score |
| 02/06/21 | Kansas City, MO | Southern Indiana 96, Rockhurst 86 | Box score |
| 02/06/21 | Liberty, MO | Indianapolis 79, William Jewell 34 | Box score |
| 02/04/21 | Liberty, MO | William Jewell 70, Southern Indiana 58 | Box score |
| 02/04/21 | Springfield, MO | Drury 80, Lindenwood 72 | Box score |
| 02/04/21 | Kirksville, MO | Indianapolis 78, Truman State 74 | Box score |
| 02/04/21 | Kansas City, MO | McKendree 62, Rockhurst 55 | Box score |
| 02/04/21 | Rolla, MO | Missouri S&T 78, Maryville 70 | Box score |
| 02/02/21 | Springfield, MO | Rockhurst 75, Drury 69 | Box score |
| 02/02/21 | Saint Charles, MO | Lindenwood 83, Illinois Springfield 74 | Box score |
| 02/02/21 | Quincy, IL | Quincy 69, Southern Indiana 61 | Box score |
| 01/30/21 | Evansville, IN | Truman State 73, Southern Indiana 67 | Box score |
| 01/30/21 | St. Louis, MO | Drury 76, Maryville 56 | Box score |
| 01/30/21 | St. Louis, MO | Rockhurst 57, Missouri-St. Louis 51 | Box score |
| 01/30/21 | Saint Charles, MO | Lindenwood 74, Southwest Baptist 63 | Box score |
| 01/30/21 | Lebanon, IL | William Jewell 80, McKendree 75 | Box score |
| 01/30/21 | Indianapolis, IN | Indianapolis 82, Quincy 57 | Box score |
| 01/28/21 | Indianapolis, IN | Illinois Springfield 69, Indianapolis 63 | Box score |
| 01/28/21 | St. Louis, MO | Southwest Baptist 100, Maryville 97 | Box score |
| 01/28/21 | Saint Charles, MO | Lindenwood 62, Rockhurst 59 | Box score |
| 01/28/21 | St. Louis, MO | Missouri-St. Louis 53, William Jewell 51 | Box score |
| 01/28/21 | Lebanon, IL | Truman State 68, McKendree 65 | Box score |
| 01/28/21 | Evansville, IN | Southern Indiana 62, Quincy 50 | Box score |
| 01/28/21 | Rolla, MO | Drury 85, Missouri S&T 66 | Box score |
| 01/26/21 | Evansville, IN | Southern Indiana 56, Indianapolis 51 | Box score |
| 01/26/21 | Saint Charles, MO | Lewis 72, Lindenwood 67 | Box score |
| 01/26/21 | St. Louis, MO | Maryville 71, Missouri-St. Louis 53 | Box score |
| 01/25/21 | Kansas City, MO | Southwest Baptist 77, Rockhurst 67 | Box score |
| 01/23/21 | Bolivar, MO | Southwest Baptist 92, Missouri S&T 86 | Box score |
| 01/23/21 | Liberty, MO | Truman State 51, William Jewell 46 | Box score |
| 01/23/21 | Quincy, IL | Quincy 68, McKendree 63 | Box score |
| 01/23/21 | Springfield, IL | Southern Indiana 77, Illinois Springfield 71 | Box score |
| 01/23/21 | Kansas City, MO | Maryville 82, Rockhurst 51 | Box score |
| 01/21/21 | Springfield, IL | Illinois Springfield 68, McKendree 58 | Box score |
| 01/21/21 | Kansas City, MO | Rockhurst 82, Missouri S&T 57 | Box score |
| 01/21/21 | Romeoville, IL | Southern Indiana 64, Lewis 59 | Box score |
| 01/21/21 | Liberty, MO | William Jewell 59, Maryville 54 | Box score |
| 01/21/21 | Quincy, IL | Missouri-St. Louis 70, Quincy 49 | Box score |
| 01/19/21 | Kirksville, MO | Truman State 75, Missouri-St. Louis 63 | Box score |
| 01/19/21 | Springfield, IL | Indianapolis 71, Illinois Springfield 63 | Box score |
| 01/16/21 | Romeoville, IL | Lewis 73, Indianapolis 64 | Box score |
| 01/16/21 | Rolla, MO | William Jewell 73, Missouri S&T 67 | Box score |
| 01/16/21 | Kirksville, MO | Truman State 83, Maryville 72 | Box score |
| 01/16/21 | St. Louis, MO | Missouri-St. Louis 85, Illinois Springfield 56 | Box score |
| 01/14/21 | Kirksville, MO | Truman State 83, Missouri S&T 71 | Box score |
| 01/14/21 | Romeoville, IL | Illinois Springfield 63, Lewis 62 | Box score |
| 01/14/21 | Indianapolis, IN | McKendree 76, Indianapolis 63 | Box score |
| 01/14/21 | Quincy, IL | Maryville 80, Quincy 51 | Box score |
| 01/12/21 | Springfield, IL | Lewis 78, Illinois Springfield 73 | Box score |
| 01/12/21 | St. Louis, MO | Missouri-St. Louis 77, Southwest Baptist 68 | Box score |
| 01/12/21 | St. Louis, MO | Maryville 74, Quincy 70 | Box score |
| 01/09/21 | Lebanon, IL | Lewis 77, McKendree 65 | Box score |
| 01/09/21 | Bolivar, MO | Southwest Baptist 66, William Jewell 60 | Box score |
| 01/09/21 | Rolla, MO | Missouri S&T 76, Quincy 61 | Box score |
| 01/09/21 | St. Louis, MO | Maryville 75, Illinois Springfield 45 | Box score |
| 01/09/21 | St. Louis, MO | Missouri-St. Louis 75, Indianapolis 57 | Box score |
| 01/07/21 | St. Louis, MO | Lewis 80, Maryville 65 | Box score |
| 01/06/21 | Springfield, MO | Drury 96, McKendree 62 | Box score |
| 01/06/21 | Kirksville, MO | Truman State 77, William Jewell 63 | Box score |
| 01/06/21 | Bolivar, MO | Indianapolis 72, Southwest Baptist 61 | Box score |
| 01/05/21 | Romeoville, IL | Lewis 87, Missouri-St. Louis 85 | Box score |
| 01/03/21 | Rolla, MO | Illinois Springfield 72, Missouri S&T 61 | Box score |
| 01/03/21 | Springfield, MO | Drury 92, Maryville 59 | Box score |
| 01/03/21 | Liberty, MO | Missouri-St. Louis 86, William Jewell 58 | Box score |
| 01/03/21 | Kirksville, MO | Southern Indiana 83, Truman State 78 | Box score |
| 01/02/21 | Bolivar, MO | Lindenwood 79, Southwest Baptist 73 | Box score |
| 12/31/20 | St. Louis, MO | Truman State 67, Maryville 62 | Box score |
| 12/20/20 | Lebanon, IL | Missouri-St. Louis 80, McKendree 70 | Box score |
| 12/20/20 | Indianapolis, IN | Indianapolis 62, Southern Indiana 55 | Box score |
| 12/20/20 | Liberty, MO | William Jewell 73, Missouri S&T 62 | Box score |
| 12/18/20 | Romeoville, IL | McKendree 67, Lewis 54 | Box score |
| 12/18/20 | Springfield, MO | Drury 97, Missouri S&T 74 | Box score |
| 12/18/20 | St. Louis, MO | Missouri-St. Louis 68, Lindenwood 51 | Box score |
| 12/18/20 | Liberty, MO | William Jewell 63, Southwest Baptist 55 | Box score |
| 12/16/20 | Quincy, IL | Indianapolis 75, Quincy 67 | Box score |
| 12/16/20 | Bolivar, MO | Rockhurst 73, Southwest Baptist 49 | Box score |
| 12/14/20 | Lebanon, IL | McKendree 79, Southwest Baptist 63 | Box score |
| 12/12/20 | Kansas City, MO | Drury 76, Rockhurst 64 | Box score |
| 12/12/20 | Evansville, IN | Southern Indiana 73, McKendree 48 | Box score |
| 12/12/20 | Saint Charles, MO | Lindenwood 80, Truman State 75 | Box score |
| 12/12/20 | Quincy, IL (Pepsi | Lewis 68, Quincy 63 | Box score |
| 12/12/20 | Rolla, MO | Missouri S&T 79, Southwest Baptist 68 | Box score |
| 12/10/20 | Saint Charles, MO | Lindenwood 87, Missouri S&T 65 | Box score |
| 12/05/20 | Liberty, MO | Drury 81, William Jewell 58 | Box score |
| 12/05/20 | Evansville, IN | Southern Indiana 63, Lewis 52 | Box score |
| 12/05/20 | St. Louis, MO | Truman State 71, Missouri-St. Louis 65 | Box score |
| 12/05/20 | Rolla, MO | Rockhurst 62, Missouri S&T 59 | Box score |
| 12/05/20 | Springfield, IL | Illinois Springfield 58, Maryville 55 | Box score |
| 12/05/20 | Lebanon, IL | Indianapolis 68, McKendree 62 | Box score |
| 12/05/20 | Quincy, IL | Lindenwood 67, Quincy 41 | Box score |
| 12/03/20 | Springfield, MO | Drury 93, Southwest Baptist 59 | Box score |
| 12/03/20 | Evansville, IN | Southern Indiana 63, Illinois Springfield 49 | Box score |
| 12/03/20 | St. Louis, MO | Maryville 79, Lindenwood 67 | Box score |
| 12/03/20 | Kansas City, MO | Rockhurst 67, William Jewell 57 | Box score |
| 12/03/20 | Indianapolis, IN | Lewis 80, Indianapolis 74 | Box score |
| 12/03/20 | Rolla, MO | McKendree 62, Missouri S&T 55 | Box score |
| 12/03/20 | St. Louis, MO | Missouri-St. Louis 76, Quincy 68 | Box score |
| 11/29/20 | Lebanon, IL | Rockhurst 70, McKendree 61 | Box score |
| 11/29/20 | Evansville, IN | Southern Indiana 80, William Jewell 55 | Box score |
| 11/29/20 | St. Louis, MO | Maryville 83, Missouri S&T 71 | Box score |
| 11/29/20 | Romeoville, IL | Lewis 80, Quincy 70 | Box score |
| 11/29/20 | Saint Charles, MO | Drury 110, Lindenwood 69 | Box score |
| 11/29/20 | Indianapolis, IN | Truman State 76, Indianapolis 68 | Box score |
| 11/27/20 | Indianapolis, IN | William Jewell 63, Indianapolis 58 | Box score |
| 11/27/20 | Springfield, IL | Illinois Springfield 76, Quincy 75 | Box score |
| 11/27/20 | Evansville, IN | Southern Indiana 70, Rockhurst 55 | Box score |
| 11/27/20 | St. Louis, MO | Drury 84, Missouri-St. Louis 67 | Box score |
| 11/27/20 | Romeoville, IL | Truman State 76, Lewis 66 | Box score |